According to Biomedtracker, the "historical success rate of P2 trials is about 20%".
Source: Jason Napodano (SA).
Source: Chi Heem Wong, Kien Wei Siah, Andrew W Lo; Estimation of clinical trial success rates and related parameters; Biostatistics, Volume 20, Issue 2, April 2019, Pages 273–286, https://doi.org/10.1093/biostatistics/kxx069
Screenshot: https://academic.oup.com/biostatistics/article/20/2/273/4817524 (Table 1)
See Also: FDA Fast Track Data: https://fda.report/media/102796/New-Drug-Applications-%28NDA%29-and-Biologic-License-Applications-%28BLA%29-Approval-Times--1993-2016.pdf (more info here)
Source: Clinical Development Success Rates 2006-2015 (BIO, Biomedtracker, Amplion 2016), page 7 / figure 1.
For oncology, it's even worse. Estimates range from 5% to 13%, with 60% failure between phase 2 and 3.
Source: Why Phase 3 Clinical Trials Fail.
At Phase 3, it's only a 34% success rate.
Source: https://cctst.uc.edu/sites/default/files/2011/Slides%20Berry%202011-06-17.pdf (slide 89, regarding standard phase 2 cancer drug trials)